3PTA
Crystal structure of human DNMT1(646-1600) in complex with DNA
Summary for 3PTA
Entry DOI | 10.2210/pdb3pta/pdb |
Related | 3PT6 3PT9 |
Descriptor | DNA (cytosine-5)-methyltransferase 1, DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3'), DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3'), ... (5 entities in total) |
Functional Keywords | dnmt1, maintenance dna methylation, transferase-dna complex, transferase/dna |
Biological source | Homo sapiens (human) |
Cellular location | Nucleus: P26358 |
Total number of polymer chains | 3 |
Total formula weight | 120360.88 |
Authors | Song, J.,Patel, D.J. (deposition date: 2010-12-02, release date: 2010-12-29, Last modification date: 2024-02-21) |
Primary citation | Song, J.,Rechkoblit, O.,Bestor, T.H.,Patel, D.J. Structure of DNMT1-DNA complex reveals a role for autoinhibition in maintenance DNA methylation. Science, 331:1036-1040, 2011 Cited by PubMed: 21163962DOI: 10.1126/science.1195380 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.6 Å) |
Structure validation
Download full validation report