3PTA
Crystal structure of human DNMT1(646-1600) in complex with DNA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | DNA (cytosine-5)-methyltransferase 1 | polymer | 956 | 108060.3 | 1 | UniProt (P26358) Pfam (PF02008) Pfam (PF01426) Pfam (PF00145) In PDB | Homo sapiens (human) | Dnmt1, CXXC-type zinc finger protein 9, DNA methyltransferase HsaI, DNA MTase HsaI, M.HsaI, MCMT |
| 2 | B | DNA (5'-D(*TP*CP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*CP*CP*GP*CP*AP*GP*G)-3') | polymer | 19 | 5782.7 | 1 | |||
| 3 | C | DNA (5'-D(*CP*CP*TP*GP*CP*GP*GP*AP*GP*GP*CP*TP*CP*AP*CP*GP*GP*GP*A)-3') | polymer | 19 | 5871.8 | 1 | |||
| 4 | A | S-ADENOSYL-L-HOMOCYSTEINE | non-polymer | 384.4 | 1 | Chemie (SAH) | |||
| 5 | A | ZINC ION | non-polymer | 65.4 | 4 | Chemie (ZN) |
Sequence modifications
A: 646 - 1600 (UniProt: P26358)
| PDB | External Database | Details |
|---|---|---|
| Ser 645 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 119714.8 | |
| Non-Polymers* | Number of molecules | 5 |
| Total formula weight | 646.0 | |
| All* | Total formula weight | 120360.9 |
