3PSE

Structure of a viral OTU domain protease bound to interferon-stimulated gene 15 (ISG15)

3PSE の概要

• エントリーDOI: 10.2210/pdb3pse/pdb
• 関連するPDBエントリー: 3PT2
• 分子名称: RNA polymerase, Ubiquitin-like protein ISG15, 1.7.6 3-bromanylpropan-1-amine, ... (5 entities in total)
• 機能のキーワード: viral deubiquitinase, 3-aminopropane, intein-mediated ligation, crimean-congo hemorrhagic fever virus, hydrolase-protein binding complex, hydrolase/protein binding
• 由来する生物種: Crimean-Congo hemorrhagic fever virus; 詳細
• 細胞内の位置: Cytoplasm: P05161
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 36828.52

構造登録者

Bacik, J.P.,James, T.W.,Frias-Staheli, N.,Garcia-Sastre, A.,Mark, B.L. (登録日: 2010-12-01, 公開日: 2011-01-19, 最終更新日: 2023-09-20)

• 主引用文献: James, T.W.,Frias-Staheli, N.,Bacik, J.P.,Levingston Macleod, J.M.,Khajehpour, M.,Garcia-Sastre, A.,Mark, B.L.; Structural basis for the removal of ubiquitin and interferon-stimulated gene 15 by a viral ovarian tumor domain-containing protease.; Proc.Natl.Acad.Sci.USA, 108:2222-2227, 2011; PubMed: 21245344; DOI: 10.1073/pnas.1013388108

実験手法

X-RAY DIFFRACTION (2.3 Å)