3PHB

Crystal Structure of human purine nucleoside phosphorylase in complex with DADMe-ImmG

Summary for 3PHB

• Entry DOI: 10.2210/pdb3phb/pdb
• Related: 3PHB
• Descriptor: Purine nucleoside phosphorylase, 2-amino-7-{[(3R,4R)-3-hydroxy-4-(hydroxymethyl)pyrrolidin-1-yl]methyl}-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, PHOSPHATE ION, ... (4 entities in total)
• Functional Keywords: pnp, immucillin, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm, cytoskeleton : P00491
• Total number of polymer chains: 6
• Total formula weight: 219704.43

Authors

Ho, M.,Cassera, M.B.,Murkin, A.S.,Almo, S.C.,Schramm, V.L. (deposition date: 2010-11-03, release date: 2011-11-09, Last modification date: 2024-02-21)

• Primary citation: Ho, M.,Cassera, M.B.,Murkin, A.S.,Almo, S.C.,Schramm, V.L.; Crystal Structure of human purine nucleoside phosphorylase in complex with DADMe-ImmG; to be published,

Experimental method

X-RAY DIFFRACTION (2.3 Å)