3PFV
Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide
3PFV の概要
エントリーDOI | 10.2210/pdb3pfv/pdb |
分子名称 | E3 ubiquitin-protein ligase CBL-B, 11-meric peptide from Epidermal growth factor receptor, SODIUM ION, ... (8 entities in total) |
機能のキーワード | structural genomics, structural genomics consortium, sgc, signal transduction protein, cbl-b, sh3-binding protein, ligase-protein binding complex, ligase/protein binding |
由来する生物種 | Homo sapiens (human) 詳細 |
細胞内の位置 | Cytoplasm: Q13191 Cell membrane; Single-pass type I membrane protein. Isoform 2: Secreted: P00533 |
タンパク質・核酸の鎖数 | 4 |
化学式量合計 | 77583.04 |
構造登録者 | Chaikuad, A.,Guo, K.,Cooper, C.D.O.,Ayinampudi, V.,Krojer, T.,Muniz, J.R.C.,Vollmar, M.,Canning, P.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Bullock, A.,Structural Genomics Consortium (SGC) (登録日: 2010-10-29, 公開日: 2010-12-08, 最終更新日: 2023-12-06) |
主引用文献 | Chaikuad, A.,Guo, K.,Cooper, C.D.O.,Ayinampudi, V.,Krojer, T.,Muniz, J.R.C.,Vollmar, M.,Canning, P.,Gileadi, O.,von Delft, F.,Arrowsmith, C.H.,Weigelt, J.,Edwards, A.M.,Bountra, C.,Bullock, A.,Structural Genomics Consortium (SGC) Crystal structure of Cbl-b TKB domain in complex with EGFR pY1069 peptide To be Published, |
実験手法 | X-RAY DIFFRACTION (2.27 Å) |
構造検証レポート
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