3OWP

Human cAMP-dependent protein kinase in complex with an inhibitor

Summary for 3OWP

• Entry DOI: 10.2210/pdb3owp/pdb
• Related: 3N47 3NX8 3OOG 3OVV
• Descriptor: cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, (2S)-2-amino-N'-[(1E)-(3-bromo-4-hydroxyphenyl)methylidene]-2-phenylethanehydrazide, ... (4 entities in total)
• Functional Keywords: transferase, atp binding, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
• Biological source: Homo sapiens (human); More
• Cellular location: Cytoplasm: P17612
• Total number of polymer chains: 2
• Total formula weight: 43383.18

Authors

Koester, H.,Heine, A.,Klebe, G. (deposition date: 2010-09-20, release date: 2011-09-21, Last modification date: 2024-10-16)

• Primary citation: Koester, H.,Craan, T.,Brass, S.,Heine, A.,Klebe, G.; fragment based drug design on PKA; To be Published,

Experimental method

X-RAY DIFFRACTION (1.88 Å)