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3OVV

Human cAMP-dependent protein kinase in complex with an inhibitor

Summary for 3OVV
Entry DOI10.2210/pdb3ovv/pdb
Related3N47 3NX8 3OOG
DescriptorcAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha, N'-[(1E)-(4-hydroxyphenyl)methylidene]-2-(3-methoxyphenyl)acetohydrazide, ... (5 entities in total)
Functional Keywordstransferase, atp binding, phosphorylation, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: P17612
Total number of polymer chains2
Total formula weight43409.41
Authors
Koester, H.,Heine, A.,Klebe, G. (deposition date: 2010-09-17, release date: 2011-09-21, Last modification date: 2013-03-13)
Primary citationKoester, H.,Craan, T.,Brass, S.,Heine, A.,Klebe, G.
fragment based drug design on PKA
To be Published,
Experimental method
X-RAY DIFFRACTION (1.58 Å)
Structure validation

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