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3OVV

Human cAMP-dependent protein kinase in complex with an inhibitor

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
cAMP-dependent protein kinase catalytic subunit alphapolymer35140808.61UniProt (P17612)
Pfam (PF00069)
Homo sapiens (human)PKA C-alpha
2B
(B)
cAMP-dependent protein kinase inhibitor alphapolymer202226.41UniProt (P61925)Homo sapiensPKI-alpha, cAMP-dependent protein kinase inhibitor, muscle/brain isoform
3C
(A)
N'-[(1E)-(4-hydroxyphenyl)methylidene]-2-(3-methoxyphenyl)acetohydrazidenon-polymer284.31Chemie (1SB)
4D
(B)
(2S,3S)-butane-2,3-diolnon-polymer90.11Chemie (BUD)
5E, F
(A, B)
waterwater18.0332Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains2
Total formula weight43035.0
Non-Polymers*Number of molecules2
Total formula weight374.4
All*Total formula weight43409.4
*Water molecules are not included.

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PDB entries from 2025-07-23

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