3OGQ
Crystal Structure of 6s-98S FIV Protease with Lopinavir bound
Summary for 3OGQ
Entry DOI | 10.2210/pdb3ogq/pdb |
Related | 1B11 2HAH 3OGP |
Descriptor | FIV protease, N-{1-BENZYL-4-[2-(2,6-DIMETHYL-PHENOXY)-ACETYLAMINO]-3-HYDROXY-5-PHENYL-PENTYL}-3-METHYL-2-(2-OXO-TETRAHYDRO-PYRIMIDIN-1-YL)-BUTYRAMIDE, DIMETHYL SULFOXIDE, ... (4 entities in total) |
Functional Keywords | aspartyl protease, hiv-like fiv chimera, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Feline immunodeficiency virus (FIV) |
Total number of polymer chains | 2 |
Total formula weight | 27241.64 |
Authors | Lin, Y.-C.,Perryman, A.L.,Elder, J.H.,Stout, C.D. (deposition date: 2010-08-17, release date: 2011-06-08, Last modification date: 2024-02-21) |
Primary citation | Lin, Y.C.,Perryman, A.L.,Olson, A.J.,Torbett, B.E.,Elder, J.H.,Stout, C.D. Structural basis for drug and substrate specificity exhibited by FIV encoding a chimeric FIV/HIV protease. Acta Crystallogr.,Sect.D, 67:540-548, 2011 Cited by PubMed: 21636894DOI: 10.1107/S0907444911011681 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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