3OF0

crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain

Summary for 3OF0

• Entry DOI: 10.2210/pdb3of0/pdb
• Related: 2OIQ 3OEZ
• Descriptor: Proto-oncogene tyrosine-protein kinase Src (2 entities in total)
• Functional Keywords: c-src l317i mutant, tyrosine kinase, transferase
• Biological source: Gallus gallus (bantam,chickens)
• Cellular location: Cell membrane (By similarity): P00523
• Total number of polymer chains: 2
• Total formula weight: 65453.29

Authors

Boubeva, R.,Pernot, L.,Perozzo, R.,Scapozza, L. (deposition date: 2010-08-13, release date: 2011-08-17, Last modification date: 2023-09-06)

• Primary citation: Boubeva, R.,Pernot, L.,Cristiani, A.,Moretti, L.,Berteotti, A.,Perozzo, R.,Gervasio, F.,Scapozza, L.; a single amino-acid dictates the dynamics of the switch between active and inactive C-Src conformation; To be Published,

Experimental method

X-RAY DIFFRACTION (2.7 Å)