3OF0

crystal structure of the L317I mutant of the chicken c-Src tyrosine kinase domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Proto-oncogene tyrosine-protein kinase Src	polymer	286	32726.6	2	UniProt (P00523) Pfam (PF07714)	Gallus gallus (bantam chickens)	Proto-oncogene c-Src, pp60c-src, p60-Src
2	C, D (A, B)	water	water		18.0	241	Chemie (HOH)

Sequence modifications

A, B: 251 - 533 (UniProt: P00523)

PDB	External Database	Details
Gly 248	-	expression tag
His 249	-	expression tag
Met 250	-	expression tag
Ile 317	Leu 317	engineered mutation

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	65453.3
All*	Total formula weight	65453.3

*Water molecules are not included.