3OD4

Crystal Structure of Factor Inhibiting HIF-1 Alpha Complexed with Inhibitor

Summary for 3OD4

• Entry DOI: 10.2210/pdb3od4/pdb
• Related: 1H2K 1H2L 1H2M 1H2N 1MZF 1YCI 2CGN 2CGO 2W0X 2WA3 2WA4
• Descriptor: Hypoxia-inducible factor 1-alpha inhibitor, ZINC ION, 8-hydroxyquinoline-5-carboxylic acid, ... (6 entities in total)
• Functional Keywords: oxidoreductase, asparaginyl hydroxylase, dioxygenase, transcription, metal-binding, hif, iron, hydroxylation, oxygenase, nucleus, oxidoreductase-oxidoreductase inhibitor complex, oxidoreductase/oxidoreductase inhibitor
• Biological source: Homo sapiens (human)
• Cellular location: Nucleus (Potential): Q9NWT6
• Total number of polymer chains: 1
• Total formula weight: 41239.42

Authors

King, O.N.F.,Bashford-Rogers, R.,Maloney, D.J.,Jadhav, A.,Heightman, T.D.,Simeonov, A.,Clifton, I.J.,McDonough, M.A.,Schofield, C.J. (deposition date: 2010-08-10, release date: 2011-07-06, Last modification date: 2024-03-20)

• Primary citation: King, O.N.F.,Bashford-Rogers, R.,Maloney, D.J.,Jadhav, A.,Heightman, T.D.,Simeonov, A.,Clifton, I.J.,McDonough, M.A.,Schofield, C.J.; Crystal Structure of Factor Inhibiting HIF-1 Alpha Complexed with Inhibitor; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)