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3NKB

A 1.9A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage

Summary for 3NKB
Entry DOI10.2210/pdb3nkb/pdb
Related1CX0 1SJ3
DescriptorDNA/RNA (5'-D(*(DUR))-D(*GP*G)-R(P*CP*UP*UP*GP*CP*A)-3'), The hepatitis delta virus ribozyme, MAGNESIUM ION, ... (4 entities in total)
Functional Keywordscatalytic rna, metal-mediated catalysis, phosphodiester cleavage, dna, rna
Total number of polymer chains2
Total formula weight23636.17
Authors
Chen, J.-H.,Yajima, R.,Chadalavada, D.M.,Chase, E.,Bevilacqua, P.C.,Golden, B.L. (deposition date: 2010-06-18, release date: 2010-09-01, Last modification date: 2023-09-06)
Primary citationChen, J.H.,Yajima, R.,Chadalavada, D.M.,Chase, E.,Bevilacqua, P.C.,Golden, B.L.
A 1.9 A crystal structure of the HDV ribozyme precleavage suggests both Lewis acid and general acid mechanisms contribute to phosphodiester cleavage.
Biochemistry, 49:6508-6518, 2010
Cited by
PubMed: 20677830
DOI: 10.1021/bi100670p
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (1.916 Å)
Structure validation

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