3NJP
The Extracellular and Transmembrane Domain Interfaces in Epidermal Growth Factor Receptor Signaling
Summary for 3NJP
Entry DOI | 10.2210/pdb3njp/pdb |
Descriptor | Epidermal growth factor receptor, Epidermal growth factor, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total) |
Functional Keywords | receptor tyrosine kinase, transferase |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 4 |
Total formula weight | 151812.47 |
Authors | Lu, C.,Mi, L.-Z.,Grey, M.J.,Zhu, J.,Graef, E.,Yokoyama, S.,Springer, T.A. (deposition date: 2010-06-17, release date: 2010-10-13, Last modification date: 2023-09-06) |
Primary citation | Lu, C.,Mi, L.Z.,Grey, M.J.,Zhu, J.,Graef, E.,Yokoyama, S.,Springer, T.A. Structural evidence for loose linkage between ligand binding and kinase activation in the epidermal growth factor receptor. Mol.Cell.Biol., 30:5432-5443, 2010 Cited by PubMed: 20837704DOI: 10.1128/MCB.00742-10 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.304 Å) |
Structure validation
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