Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3N57

Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human atrial natriuretic peptide (ANP)

Summary for 3N57
Entry DOI10.2210/pdb3n57/pdb
Related1T34 1YK0 2G47 2WBY 3CWW 3H44 3N56
DescriptorInsulin-degrading enzyme, Atrial natriuretic factor, ZINC ION, ... (4 entities in total)
Functional Keywordsinsulysin, insulinase, a-beta degrading enzyme, cryptidase, hydrolase, hormone, disease mutation, diabetes mellitus, insulin, cardiac, secreted, protease, disulfide bond, metalloprotease, human insulin-degradng enzyme, metal-binding, natriuretic peptide, natriuretic factor, cardiovascular regulation, hydrolase-hormone complex, hydrolase/hormone
Biological sourceHomo sapiens (human)
More
Cellular locationCytoplasm: P14735
Secreted: P01160
Total number of polymer chains4
Total formula weight235426.98
Authors
Funke, T.,Guo, Q.,Tang, W.-J. (deposition date: 2010-05-24, release date: 2010-11-17, Last modification date: 2024-02-21)
Primary citationRalat, L.A.,Funke, T.,Ren, M.,Guo, Q.,Dickey, D.M.,Potter, L.R.,Tang, W.-J.
Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human atrial natriuretic peptide (ANP)
To be Published,
Experimental method
X-RAY DIFFRACTION (3.03 Å)
Structure validation

217705

數據於2024-03-27公開中

PDB statisticsPDBj update infoContact PDBjnumon