3N57

Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human atrial natriuretic peptide (ANP)

3N57 の概要

• エントリーDOI: 10.2210/pdb3n57/pdb
• 関連するPDBエントリー: 1T34 1YK0 2G47 2WBY 3CWW 3H44 3N56
• 分子名称: Insulin-degrading enzyme, Atrial natriuretic factor, ZINC ION, ... (4 entities in total)
• 機能のキーワード: insulysin, insulinase, a-beta degrading enzyme, cryptidase, hydrolase, hormone, disease mutation, diabetes mellitus, insulin, cardiac, secreted, protease, disulfide bond, metalloprotease, human insulin-degradng enzyme, metal-binding, natriuretic peptide, natriuretic factor, cardiovascular regulation, hydrolase-hormone complex, hydrolase/hormone
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cytoplasm: P14735; Secreted: P01160
• タンパク質・核酸の鎖数: 4
• 化学式量合計: 235426.98

構造登録者

Funke, T.,Guo, Q.,Tang, W.-J. (登録日: 2010-05-24, 公開日: 2010-11-17, 最終更新日: 2024-02-21)

• 主引用文献: Ralat, L.A.,Funke, T.,Ren, M.,Guo, Q.,Dickey, D.M.,Potter, L.R.,Tang, W.-J.; Crystal Structure of human Insulin-degrading enzyme (IDE) in complex with human atrial natriuretic peptide (ANP); To be Published,

実験手法

X-RAY DIFFRACTION (3.03 Å)