3MVB

Crystal structure of a triple RFY mutant of human MTERF1 bound to the termination sequence

Summary for 3MVB

• Entry DOI: 10.2210/pdb3mvb/pdb
• Related: 3MVA
• Descriptor: Transcription termination factor, mitochondrial, 5'-D(*AP*TP*TP*AP*CP*CP*GP*GP*GP*CP*TP*CP*TP*GP*CP*CP*AP*TP*CP*TP*TP*A)-3', 5'-D(*TP*AP*AP*GP*AP*TP*GP*GP*CP*AP*GP*AP*GP*CP*CP*CP*GP*GP*TP*AP*AP*T)-3', ... (4 entities in total)
• Functional Keywords: all alpha-helix, protein-dna, transcription factor, termination, mitochondria, transcription-dna complex, transcription/dna
• Biological source: Homo sapiens (human)
• Cellular location: Mitochondrion: Q99551
• Total number of polymer chains: 3
• Total formula weight: 52574.02

Authors

Yakubovskaya, E.,Mejia, E.,Byrnes, J.,Hambardjieva, E.,Garcia-Diaz, M. (deposition date: 2010-05-03, release date: 2010-06-30, Last modification date: 2024-02-21)

• Primary citation: Yakubovskaya, E.,Mejia, E.,Byrnes, J.,Hambardjieva, E.,Garcia-Diaz, M.; Helix unwinding and base flipping enable human MTERF1 to terminate mitochondrial transcription.; Cell(Cambridge,Mass.), 141:982-993, 2010; PubMed: 20550934; DOI: 10.1016/j.cell.2010.05.018

Experimental method

X-RAY DIFFRACTION (2.786 Å)