3MIP
I-MsoI re-designed for altered DNA cleavage specificity (-8GCG)
Summary for 3MIP
Entry DOI | 10.2210/pdb3mip/pdb |
Related | 3ko2 3MIS |
Descriptor | Mso-8G, DNA (5'-D(*GP*CP*AP*GP*GP*CP*GP*GP*TP*CP*GP*TP*GP*AP*GP*AP*CP*CP*GP*CP*TP*CP*CP*G)-3'), DNA (5'-D(*CP*GP*GP*AP*GP*CP*GP*GP*TP*CP*TP*CP*AP*CP*GP*AP*CP*CP*GP*CP*CP*TP*GP*C)-3'), ... (5 entities in total) |
Functional Keywords | protein-dna complex, homing nuclease, rosetta design, de novo protein-dna complex, de novo protein/dna |
Biological source | synthetic construct (artificial gene) |
Total number of polymer chains | 4 |
Total formula weight | 52292.87 |
Authors | Taylor, G.K.,Stoddard, B.L. (deposition date: 2010-04-11, release date: 2010-05-19, Last modification date: 2024-02-21) |
Primary citation | Ashworth, J.,Taylor, G.K.,Havranek, J.J.,Quadri, S.A.,Stoddard, B.L.,Baker, D. Computational reprogramming of homing endonuclease specificity at multiple adjacent base pairs. Nucleic Acids Res., 38:5601-5608, 2010 Cited by PubMed: 20435674DOI: 10.1093/nar/gkq283 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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