3MBW

Crystal structure of the human ephrin A2 LBD and CRD domains in complex with ephrin A1

3MBW の概要

• エントリーDOI: 10.2210/pdb3mbw/pdb
• 関連するPDBエントリー: 3C8X 3CZU 3FL7
• 分子名称: Ephrin type-A receptor 2, Ephrin-A1, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (5 entities in total)
• 機能のキーワード: atp-binding, kinase, nucleotide-binding, receptor, transferase, phosphorylation, transmembrane, tyrosine-protein kinase, glycoprotein, cysteine-rich domain, phosphoprotein, gpi-anchor, lipoprotein, transferase-signaling protein complex, structural genomics consortium, sgc, transferase/signaling protein
• 由来する生物種: Homo sapiens (human); 詳細
• 細胞内の位置: Cell membrane; Single-pass type I membrane protein: P29317; Cell membrane; Lipid-anchor, GPI-anchor. Ephrin-A1, secreted form: Secreted: P20827
• タンパク質・核酸の鎖数: 2
• 化学式量合計: 58734.38

構造登録者

Walker, J.R.,Yermekbayeva, L.,Seitova, A.,Butler-Cole, C.,Bountra, C.,Weigelt, J.,Arrowsmith, C.H.,Edwards, A.M.,Bochkarev, A.,Dhe-Paganon, S.,Structural Genomics Consortium (SGC) (登録日: 2010-03-26, 公開日: 2010-06-09, 最終更新日: 2023-09-06)

• 主引用文献: Himanen, J.P.,Yermekbayeva, L.,Janes, P.W.,Walker, J.R.,Xu, K.,Atapattu, L.,Rajashankar, K.R.,Mensinga, A.,Lackmann, M.,Nikolov, D.B.,Dhe-Paganon, S.; Architecture of Eph receptor clusters.; Proc.Natl.Acad.Sci.USA, 107:10860-10865, 2010; PubMed: 20505120; DOI: 10.1073/pnas.1004148107

実験手法

X-RAY DIFFRACTION (2.81 Å)