3LDW
Crystal Structure of Plasmodium vivax geranylgeranylpyrophosphate synthase PVX_092040 with zoledronate and IPP bound
Summary for 3LDW
Entry DOI | 10.2210/pdb3ldw/pdb |
Descriptor | Farnesyl pyrophosphate synthase, ZOLEDRONIC ACID, 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPHATE, ... (7 entities in total) |
Functional Keywords | malaria, farnesyl pyrophosphate synthase diphosphate, lyase, structural genomics, isoprene biosynthesis, transferase, structural genomics consortium, sgc |
Biological source | Plasmodium vivax |
Total number of polymer chains | 4 |
Total formula weight | 187627.81 |
Authors | Wernimont, A.K.,Lew, J.,Zhao, Y.,Kozieradzki, I.,Cossar, D.,Schapira, M.,Bochkarev, A.,Arrowsmith, C.H.,Bountra, C.,Weigelt, J.,Edwards, A.M.,Hui, R.,Artz, J.D.,Structural Genomics Consortium (SGC) (deposition date: 2010-01-13, release date: 2010-11-17, Last modification date: 2024-02-21) |
Primary citation | Artz, J.D.,Wernimont, A.K.,Dunford, J.E.,Schapira, M.,Dong, A.,Zhao, Y.,Lew, J.,Russell, R.G.,Ebetino, F.H.,Oppermann, U.,Hui, R. Molecular characterization of a novel geranylgeranyl pyrophosphate synthase from Plasmodium parasites. J.Biol.Chem., 286:3315-3322, 2011 Cited by PubMed: 21084289DOI: 10.1074/jbc.M109.027235 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.47 Å) |
Structure validation
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