3L5H

Crystal structure of the full ectodomain of human gp130: New insights into the molecular assembly of receptor complexes

3L5H の概要

• エントリーDOI: 10.2210/pdb3l5h/pdb
• 関連するPDBエントリー: 3L5I 3L5J
• 分子名称: Interleukin-6 receptor subunit beta, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• 機能のキーワード: ig-like, fniii, cell membrane, disulfide bond, glycoprotein, immunoglobulin domain, membrane, phosphoprotein, receptor, secreted, transmembrane, immune system
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 71026.32

構造登録者

Xu, Y.,Garrett, T.P.J.,Zhang, J.G. (登録日: 2009-12-21, 公開日: 2010-05-19, 最終更新日: 2020-07-29)

• 主引用文献: Xu, Y.,Kershaw, N.J.,Luo, C.S.,Soo, P.,Pocock, M.J.,Czabotar, P.E.,Hilton, D.J.,Nicola, N.A.,Garrett, T.P.,Zhang, J.G.; Crystal structure of the entire ectodomain of gp130: insights into the molecular assembly of the tall cytokine receptor complexes.; J.Biol.Chem., 285:21214-21218, 2010; PubMed: 20489211; DOI: 10.1074/jbc.C110.129502

実験手法

X-RAY DIFFRACTION (3.6 Å)