3KYD
Human SUMO E1~SUMO1-AMP tetrahedral intermediate mimic
Summary for 3KYD
Entry DOI | 10.2210/pdb3kyd/pdb |
Related | 3KYC |
Descriptor | SUMO-activating enzyme subunit 1, SUMO-activating enzyme subunit 2, Small ubiquitin-related modifier 1, ... (7 entities in total) |
Functional Keywords | e1, sumo, ubiquitin, thioester, adenylation, inhibitor, tetrahedral intermediate, ligase, nucleus, phosphoprotein, ubl conjugation pathway, atp-binding, nucleotide-binding, isopeptide bond, membrane |
Biological source | Homo sapiens (human) More |
Cellular location | Nucleus : Q9UBE0 Cytoplasm: Q9UBT2 Nucleus membrane: P63165 |
Total number of polymer chains | 3 |
Total formula weight | 113909.89 |
Authors | Lima, C.D. (deposition date: 2009-12-05, release date: 2010-02-16, Last modification date: 2024-03-13) |
Primary citation | Olsen, S.K.,Capili, A.D.,Lu, X.,Tan, D.S.,Lima, C.D. Active site remodelling accompanies thioester bond formation in the SUMO E1. Nature, 463:906-912, 2010 Cited by PubMed: 20164921DOI: 10.1038/nature08765 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.61 Å) |
Structure validation
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