Loading
PDBj
メニューPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

3KRW

Human GRK2 in complex with Gbetgamma subunits and balanol (soak)

3KRW の概要
エントリーDOI10.2210/pdb3krw/pdb
関連するPDBエントリー1BX6 1OMW 3CIK 3KRX
分子名称Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... (6 entities in total)
機能のキーワードprotein kinase, inhibitor, complex, wd40, ph domain, rgs homology domain, atp-binding, kinase, nucleotide-binding, phosphoprotein, polymorphism, serine/threonine-protein kinase, transferase, acetylation, transducer, wd repeat, cell membrane, lipoprotein, membrane, methylation, prenylation, protein binding
由来する生物種Homo sapiens (human)
詳細
細胞内の位置Cell membrane; Lipid-anchor; Cytoplasmic side (Potential): P63212
タンパク質・核酸の鎖数3
化学式量合計125959.85
構造登録者
Tesmer, J.J.G.,Tesmer, V.M. (登録日: 2009-11-19, 公開日: 2010-02-16, 最終更新日: 2023-09-06)
主引用文献Tesmer, J.J.,Tesmer, V.M.,Lodowski, D.T.,Steinhagen, H.,Huber, J.
Structure of human g protein-coupled receptor kinase 2 in complex with the kinase inhibitor balanol.
J.Med.Chem., 53:1867-1870, 2010
Cited by
PubMed: 20128603
DOI: 10.1021/jm9017515
主引用文献が同じPDBエントリー
実験手法
X-RAY DIFFRACTION (2.9 Å)
構造検証レポート
Validation report summary of 3krw
検証レポート(詳細版)ダウンロードをダウンロード

225158

件を2024-09-18に公開中

PDB statisticsPDBj update infoContact PDBjnumon