3KRW
Human GRK2 in complex with Gbetgamma subunits and balanol (soak)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Beta-adrenergic receptor kinase 1 | polymer | 688 | 79561.4 | 1 | UniProt (P25098) Pfam (PF00615) Pfam (PF00069) Pfam (PF00169) | Homo sapiens (human) | Beta-ARK-1, G-protein coupled receptor kinase 2 |
| 2 | B (B) | Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1 | polymer | 340 | 37416.9 | 1 | UniProt (P62871) Pfam (PF00400) | Bos taurus (bovine cow domestic cattle domestic cow) | Transducin beta chain 1 |
| 3 | C (G) | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2 | polymer | 74 | 8406.7 | 1 | UniProt (P63212) Pfam (PF00631) | Bos taurus (bovine cow domestic cattle domestic cow) | G gamma-I |
| 4 | D (A) | BALANOL | non-polymer | 550.5 | 1 | Chemie (BA1) | |||
| 5 | E (A) | MAGNESIUM ION | non-polymer | 24.3 | 1 | Chemie (MG) | |||
| 6 | F (A) | water | water | 18.0 | 3 | Chemie (HOH) |
Sequence modifications
G: 1 - 68 (UniProt: P63212)
| PDB | External Database | Details |
|---|---|---|
| His -5 | - | expression tag |
| His -4 | - | expression tag |
| His -3 | - | expression tag |
| His -2 | - | expression tag |
| His -1 | - | expression tag |
| His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 3 |
| Total formula weight | 125385.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 574.8 | |
| All* | Total formula weight | 125959.9 |
