3KNT
Crystal structure of Methanocaldococcus jannaschii 8-oxoguanine glycosylase/lyase in complex with 15mer DNA containing 8-oxoguanine
Summary for 3KNT
Entry DOI | 10.2210/pdb3knt/pdb |
Descriptor | N-glycosylase/DNA lyase, 5'-D(*AP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3', 5'-D(*TP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3', ... (5 entities in total) |
Functional Keywords | protein-dna complex, ogg, helix-hairpin-helix, glycosylase, 8-oxoguanine, 8-oxog, dna repair, dna damage, glycosidase, multifunctional enzyme, nuclease, hydrolase, lyase-dna complex, lyase/dna |
Biological source | Methanocaldococcus jannaschii (Methanococcus jannaschii) More |
Total number of polymer chains | 12 |
Total formula weight | 136351.04 |
Authors | Faucher, F.,Doublie, S. (deposition date: 2009-11-12, release date: 2010-02-02, Last modification date: 2023-09-06) |
Primary citation | Faucher, F.,Wallace, S.S.,Doublie, S. The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction. J.Mol.Biol., 397:46-56, 2010 Cited by PubMed: 20083120DOI: 10.1016/j.jmb.2010.01.024 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.7 Å) |
Structure validation
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