3KNT
Crystal structure of Methanocaldococcus jannaschii 8-oxoguanine glycosylase/lyase in complex with 15mer DNA containing 8-oxoguanine
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | N-glycosylase/DNA lyase | polymer | 207 | 24868.8 | 4 | UniProt (Q58134) Pfam (PF22175) In PDB | Methanocaldococcus jannaschii (Methanococcus jannaschii) | 8-oxoguanine DNA glycosylase, DNA-(apurinic or apyrimidinic site) lyase, AP lyase |
| 2 | E, G, I, K | 5'-D(*AP*CP*GP*TP*CP*CP*AP*(8OG)P*GP*TP*CP*TP*AP*CP*C)-3' | polymer | 15 | 4545.9 | 4 | |||
| 3 | F, H, J, L | 5'-D(*TP*GP*GP*TP*AP*GP*AP*CP*CP*TP*GP*GP*AP*CP*G)-3' | polymer | 15 | 4650.0 | 4 | |||
| 4 | A, B, C, D | SODIUM ION | non-polymer | 23.0 | 4 | Chemie (NA) | |||
| 5 | water | water | 18.0 | 35 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 207 (UniProt: Q58134)
| PDB | External Database | Details |
|---|---|---|
| Gln 129 | Lys 129 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 12 |
| Total formula weight | 136259.1 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 92.0 | |
| All* | Total formula weight | 136351.0 |
