3JZQ

Human MDMX liganded with a 12mer peptide inhibitor (pDIQ)

3JZQ の概要

関連するPDBエントリー3JZO 3JZP 3JZR 3JZS
分子名称Protein Mdm4, pDIQ peptide (12mer), SULFATE ION, ... (4 entities in total)
機能のキーワードcell cycle, p53-binding protein mdm4, double minute 4 protein, alternative splicing, metal-binding, nucleus, polymorphism, zinc, zinc-finger
由来する生物種Homo sapiens (human)
細胞内の位置Nucleus O15151
ポリマー鎖数4
分子量合計23545.23
構造登録者
Schonbrunn, E.,Phan, J. (登録日: 2009-09-24, 公開日: 2009-11-10, 最終更新日: 2011-07-13)
主引用文献
Phan, J.,Li, Z.,Kasprzak, A.,Li, B.,Sebti, S.,Guida, W.,Schonbrunn, E.,Chen, J.
Structure-based design of high affinity peptides inhibiting the interaction of p53 with MDM2 and MDMX.
J.Biol.Chem., 285:2174-2183, 2010
PubMed: 19910468 (主引用文献が同じPDBエントリー)
DOI: 10.1074/jbc.M109.073056
MImport into Mendeley
実験手法
X-RAY DIFFRACTION (1.8 Å)
NMR情報
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構造検証レポート

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.224600.6%3.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
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