3J6B

Structure of the yeast mitochondrial large ribosomal subunit

これはPDB形式変換不可エントリーです。

3J6B の概要

• エントリーDOI: 10.2210/pdb3j6b/pdb
• EMDBエントリー: 2566
• 分子名称: 21S ribosomal RNA, 54S ribosomal protein L10, mitochondrial, 54S ribosomal protein L16, mitochondrial, ... (44 entities in total)
• 機能のキーワード: mitochondrial ribosome, large subunit, protein-rna complex, ribosome
• 由来する生物種: Saccharomyces cerevisiae (yeast); 詳細
• タンパク質・核酸の鎖数: 41
• 化学式量合計: 2040157.94

構造登録者

Amunts, A.,Brown, A.,Bai, X.C.,Llacer, J.L.,Hussain, T.,Emsley, P.,Long, F.,Murshudov, G.,Scheres, S.H.W.,Ramakrishnan, V. (登録日: 2014-01-22, 公開日: 2014-04-09, 最終更新日: 2024-02-21)

主引用文献

Amunts, A.,Brown, A.,Bai, X.C.,Llacer, J.L.,Hussain, T.,Emsley, P.,Long, F.,Murshudov, G.,Scheres, S.H.,Ramakrishnan, V.
Structure of the yeast mitochondrial large ribosomal subunit.
Science, 343:1485-1489, 2014

PubMed Abstract: Mitochondria have specialized ribosomes that have diverged from their bacterial and cytoplasmic counterparts. We have solved the structure of the yeast mitoribosomal large subunit using single-particle cryo-electron microscopy. The resolution of 3.2 angstroms enabled a nearly complete atomic model to be built de novo and refined, including 39 proteins, 13 of which are unique to mitochondria, as well as expansion segments of mitoribosomal RNA. The structure reveals a new exit tunnel path and architecture, unique elements of the E site, and a putative membrane docking site.

PubMed: 24675956
DOI: 10.1126/science.1249410

実験手法

ELECTRON MICROSCOPY (3.2 Å)