3IX9

Crystal structure of Streptococcus pneumoniae dihydrofolate reductase - Sp9 mutant

Summary for 3IX9

Entry DOI	10.2210/pdb3ix9/pdb
Descriptor	Dihydrofolate reductase, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, METHOTREXATE, ... (4 entities in total)
Functional Keywords	central beta sheet surrounded by 4 alpha helices, oxidoreductase
Biological source	Streptococcus pneumoniae
Total number of polymer chains	2
Total formula weight	46860.24
Authors	Yennawar, N.H. (deposition date: 2009-09-03, release date: 2010-02-02, Last modification date: 2023-09-06)
Primary citation	Lee, J.,Yennawar, N.H.,Gam, J.,Benkovic, S.J. Kinetic and structural characterization of dihydrofolate reductase from Streptococcus pneumoniae Biochemistry, 49:195-206, 2010 Cited by PubMed: 19950924 DOI: 10.1021/bi901614m PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation