3IR0

Crystal Structure of Human Insulin complexed with Cu+2 metal ion

Summary for 3IR0

• Entry DOI: 10.2210/pdb3ir0/pdb
• Related: 1MSO 1TRZ 2QIU 2R34 2R35 2R36
• Descriptor: Insulin A chain, Insulin B chain, COPPER (II) ION, ... (4 entities in total)
• Functional Keywords: insulin, metal binding, coordination, confromation, bilogical role, carbohydrate metabolism, cleavage on pair of basic residues, diabetes mellitus, disease mutation, disulfide bond, glucose metabolism, hormone, secreted
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted: P01308 P01308
• Total number of polymer chains: 24
• Total formula weight: 70574.36

Authors

Raghavendra, N.,Pattabhi, V.,Rajan, S.S. (deposition date: 2009-08-21, release date: 2010-09-01, Last modification date: 2023-11-01)

• Primary citation: Raghavendra, N.,Pattabhi, V.,Rajan, S.S.; Metal induced structural changes observed in Human insulin; To be Published,

Experimental method

X-RAY DIFFRACTION (2.2 Å)