3IOG
Crystal structure of CphA N220G mutant with inhibitor 18
Summary for 3IOG
Entry DOI | 10.2210/pdb3iog/pdb |
Related | 1x8g 1x8h 1x8i 3F9O 3FAI 3IOF |
Descriptor | Beta-lactamase, ZINC ION, GLYCEROL, ... (6 entities in total) |
Functional Keywords | hydrolase, antibiotic resistance, metal-binding |
Biological source | Aeromonas hydrophila |
Cellular location | Periplasm (Probable): P26918 |
Total number of polymer chains | 1 |
Total formula weight | 26166.75 |
Authors | Delbruck, H.,Bebrone, C.,Hoffmann, K.M.V. (deposition date: 2009-08-14, release date: 2010-06-23, Last modification date: 2023-11-01) |
Primary citation | Lassaux, P.,Hamel, M.,Gulea, M.,Delbruck, H.,Mercuri, P.S.,Horsfall, L.,Dehareng, D.,Kupper, M.,Frere, J.-M.,Hoffmann, K.,Galleni, M.,Bebrone, C. Mercaptophosphonate Compounds as Broad-Spectrum Inhibitors of the Metallo-beta-lactamases J.Med.Chem., 53:4862-4876, 2010 Cited by PubMed: 20527888DOI: 10.1021/jm100213c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.41 Å) |
Structure validation
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