3F9O

Crystal Structure of the Di-Zinc Carbapenemase CphA from Aeromonas Hydrophila

Summary for 3F9O

• Entry DOI: 10.2210/pdb3f9o/pdb
• Related: 1X8G 1X8H 1X8I 2GKL 2QDS 3FAI
• Descriptor: Beta-lactamase, SULFATE ION, CARBONATE ION, ... (6 entities in total)
• Functional Keywords: hydrolase, antibiotic resistance, metal-binding
• Biological source: Aeromonas hydrophila
• Cellular location: Periplasm (Probable): P26918
• Total number of polymer chains: 1
• Total formula weight: 26134.03

Authors

Delbruck, H.,Hoffmann, K.M.V. (deposition date: 2008-11-14, release date: 2009-09-01, Last modification date: 2023-11-01)

• Primary citation: Bebrone, C.,Delbruck, H.,Kupper, M.B.,Schlomer, P.,Willmann, C.,Frere, J.-M.,Fischer, R.,Galleni, M.,Hoffmann, K.M.V.; The structure of the dizinc subclass B2 metallo-beta-lactamase CphA reveals that the second inhibitory zinc ion binds in the histidine site; Antimicrob.Agents Chemother., 53:4464-4471, 2009; PubMed: 19651913; DOI: 10.1128/AAC.00288-09

Experimental method

X-RAY DIFFRACTION (2.03 Å)