3INL
Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1
Summary for 3INL
Entry DOI | 10.2210/pdb3inl/pdb |
Related | 3INJ |
Descriptor | Aldehyde dehydrogenase, mitochondrial, SODIUM ION, 1,2-ETHANEDIOL, ... (5 entities in total) |
Functional Keywords | oxidoreductase, aldh, e487k, rossmann fold, alda-1, activator, mitochondrion, nad, transit peptide |
Biological source | Homo sapiens (human) |
Cellular location | Mitochondrion matrix: P05091 |
Total number of polymer chains | 8 |
Total formula weight | 440570.36 |
Authors | Perez-Miller, S.,Hurley, T.D. (deposition date: 2009-08-12, release date: 2010-01-12, Last modification date: 2024-02-21) |
Primary citation | Perez-Miller, S.,Younus, H.,Vanam, R.,Chen, C.H.,Mochly-Rosen, D.,Hurley, T.D. Alda-1 is an agonist and chemical chaperone for the common human aldehyde dehydrogenase 2 variant. Nat.Struct.Mol.Biol., 17:159-164, 2010 Cited by PubMed: 20062057DOI: 10.1038/nsmb.1737 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.862 Å) |
Structure validation
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