3INL
Human Mitochondrial Aldehyde Dehydrogenase Asian Variant, ALDH2*2, complexed with agonist Alda-1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D, E... (A, B, C, D, E...) | Aldehyde dehydrogenase, mitochondrial | polymer | 500 | 54483.6 | 8 | UniProt (P05091) Pfam (PF00171) | Homo sapiens (human) | ALDH class 2, ALDHI, ALDH-E2 |
| 2 | BA, FA, I, MA, Q... (D, E, A, F, B...) | SODIUM ION | non-polymer | 23.0 | 8 | Chemie (NA) | |||
| 3 | AB, BB, CA, DA, GA... (H, D, E, A, F...) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 31 | Chemie (EDO) | |||
| 4 | AA, CB, EA, KA, P... (C, H, D, E, A...) | N-(1,3-benzodioxol-5-ylmethyl)-2,6-dichlorobenzamide | non-polymer | 324.2 | 8 | Chemie (BXB) | |||
| 5 | DB, EB, FB, GB, HB... (A, B, C, D, E...) | water | water | 18.0 | 3408 | Chemie (HOH) |
Sequence modifications
A, B, C, D, E, F, G, H: 1 - 500 (UniProt: P05091)
| PDB | External Database | Details |
|---|---|---|
| Ser 302 | Cys 319 | engineered mutation |
| Lys 487 | Glu 504 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 8 |
| Total formula weight | 435869.1 | |
| Non-Polymers* | Number of molecules | 47 |
| Total formula weight | 4701.3 | |
| All* | Total formula weight | 440570.4 |
