3IIQ
Crystallographic analysis of bacterial signal peptidase in ternary complex with Arylomycin A2 and a beta-sultam inhibitor
Summary for 3IIQ
Entry DOI | 10.2210/pdb3iiq/pdb |
Related | 1B12 1KN9 1T7D |
Related PRD ID | PRD_000117 |
Descriptor | SIGNAL PEPTIDASE I, ARYLOMYCIN A2, 4-[(1,1-dioxido-1,2-thiazetidin-2-yl)carbonyl]morpholine, ... (8 entities in total) |
Functional Keywords | ser/lys dyad, lipopeptide, serine protease, biaryl bridge, morpholino beta-sultam, antibiotic, peptidase, hydrolase-antibiotic-inhibitor complex, hydrolase/antibiotic/inhibitor |
Biological source | ESCHERICHIA COLI More |
Cellular location | Cell inner membrane; Multi-pass membrane protein: P00803 |
Total number of polymer chains | 4 |
Total formula weight | 59219.29 |
Authors | Paetzel, M. (deposition date: 2009-08-03, release date: 2009-09-01, Last modification date: 2023-09-06) |
Primary citation | Luo, C.,Roussel, P.,Dreier, J.,Page, M.G.,Paetzel, M. Crystallographic Analysis of Bacterial Signal Peptidase in Ternary Complex with Arylomycin A2 and a Beta-Sultam Inhibitor. Biochemistry, 48:8976-, 2009 Cited by PubMed: 19655811DOI: 10.1021/BI9009538 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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