3IIQ
Crystallographic analysis of bacterial signal peptidase in ternary complex with Arylomycin A2 and a beta-sultam inhibitor
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | SIGNAL PEPTIDASE I | polymer | 249 | 27966.7 | 2 | UniProt (P00803) Pfam (PF10502) | ESCHERICHIA COLI | SPASE I, LEADER PEPTIDASE I |
| 2 | C, D (C, D) | ARYLOMYCIN A2 | polymer | 6 | 644.7 | 2 | NOR (NOR01115) BIRD (PRD_000117) | STREPTOMYCES SP. | |
| 3 | E, M (A, B) | 4-[(1,1-dioxido-1,2-thiazetidin-2-yl)carbonyl]morpholine | non-polymer | 220.2 | 2 | Chemie (JZA) | |||
| 4 | F, N (A, B) | FRAGMENT OF TRITON X-100 | non-polymer | 352.5 | 2 | Chemie (TRT) | |||
| 5 | G, H, I, J (A) | GLYCEROL | non-polymer | 92.1 | 4 | Chemie (GOL) | |||
| 6 | K, L (A) | ACETONITRILE | non-polymer | 41.1 | 2 | Chemie (CCN) | |||
| 7 | O, P (C, D) | 10-METHYLUNDECANOIC ACID | non-polymer | 200.3 | 2 | BIRD (PRD_000117) Chemie (M12) | |||
| 8 | Q, R, S, T (A, B, C, D) | water | water | 18.0 | 246 | Chemie (HOH) |
Sequence modifications
A, B: 76 - 323 (UniProt: P00803)
C, D: 1 - 6 (NOR: NOR01115)
| PDB | External Database | Details |
|---|---|---|
| Met 75 | - | initiating methionine |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 57222.7 | |
| Non-Polymers* | Number of molecules | 12 |
| Total formula weight | 1996.6 | |
| All* | Total formula weight | 59219.3 |
