3IER

Firefly luciferase apo structure (P41 form) with PEG 400 bound

Summary for 3IER

Entry DOI	10.2210/pdb3ier/pdb
Related	3IEP 3IES
Descriptor	Luciferin 4-monooxygenase, TETRAETHYLENE GLYCOL (3 entities in total)
Functional Keywords	oxidoreductase, monooxygenase, photoprotein, luminescence, atp-binding, magnesium, metal-binding, nucleotide-binding, peroxisome
Biological source	Photinus pyralis (North American firefly)
Cellular location	Peroxisome : P08659
Total number of polymer chains	1
Total formula weight	61112.31
Authors	Lovell, S.,Battaile, K.P.,Auld, D.S.,Thorne, N.,Lea, W.A.,Maloney, D.J.,Shen, M.,Raj, G.,Thomas, C.J.,Simeonov, A.,Hanzlik, R.P.,Inglese, J. (deposition date: 2009-07-23, release date: 2010-02-16, Last modification date: 2023-09-06)
Primary citation	Auld, D.S.,Lovell, S.,Thorne, N.,Lea, W.A.,Maloney, D.J.,Shen, M.,Rai, G.,Battaile, K.P.,Thomas, C.J.,Simeonov, A.,Hanzlik, R.P.,Inglese, J. Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124. Proc.Natl.Acad.Sci.USA, 107:4878-4883, 2010 Cited by PubMed: 20194791 DOI: 10.1073/pnas.0909141107 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.05 Å)

Structure validation