Firefly luciferase apo structure (P41 form)

Summary for 3IEP

Related3IER 3IES
DescriptorLuciferin 4-monooxygenase (2 entities in total)
Functional Keywordsoxidoreductase, monooxygenase, photoprotein, luminescence, atp-binding, magnesium, metal-binding, nucleotide-binding, peroxisome
Biological sourcePhotinus pyralis (North American firefly)
Cellular locationPeroxisome  P08659
Total number of polymer chains1
Total molecular weight60918.09
Lovell, S.,Battaile, K.P.,Auld, D.S.,Thorne, N.,Lea, W.A.,Maloney, D.J.,Shen, M.,Raj, G.,Thomas, C.J.,Simeonov, A.,Hanzlik, R.P.,Inglese, J. (deposition date: 2009-07-23, release date: 2010-02-16, Last modification date: 2017-11-01)
Primary citation
Auld, D.S.,Lovell, S.,Thorne, N.,Lea, W.A.,Maloney, D.J.,Shen, M.,Rai, G.,Battaile, K.P.,Thomas, C.J.,Simeonov, A.,Hanzlik, R.P.,Inglese, J.
Molecular basis for the high-affinity binding and stabilization of firefly luciferase by PTC124.
Proc.Natl.Acad.Sci.USA, 107:4878-4883, 2010
PubMed: 20194791 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.0909141107
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.225502.5%2.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report