3ID8

Ternary complex of human pancreatic glucokinase crystallized with activator, glucose and AMP-PNP

3ID8 の概要

• エントリーDOI: 10.2210/pdb3id8/pdb
• 関連するPDBエントリー: 1V4S 3F9M 3FGU 3IDH
• 分子名称: Glucokinase, alpha-D-glucopyranose, 2-AMINO-4-FLUORO-5-[(1-METHYL-1H-IMIDAZOL-2-YL)SULFANYL]-N-(1,3-THIAZOL-2-YL)BENZAMIDE, ... (7 entities in total)
• 機能のキーワード: glucokinase, hexokinase iv, atp-binding, diabetes mellitus, disease mutation, glycolysis, kinase, nucleotide-binding, transferase
• 由来する生物種: Homo sapiens (human)
• タンパク質・核酸の鎖数: 1
• 化学式量合計: 54095.35

構造登録者

Petit, P.,Gluais, L.,Lagarde, A.,Boutin, J.A.,Ferry, G.,Vuillard, L. (登録日: 2009-07-20, 公開日: 2010-07-28, 最終更新日: 2023-11-01)

• 主引用文献: Petit, P.,Antoine, M.,Ferry, G.,Boutin, J.A.,Lagarde, A.,Gluais, L.,Vincentelli, R.,Vuillard, L.; The active conformation of human glucokinase is not altered by allosteric activators; Acta Crystallogr.,Sect.D, 67:929-935, 2011; PubMed: 22101819; DOI: 10.1107/S0907444911036729

実験手法

X-RAY DIFFRACTION (2.4 Å)