3I7H

Crystal Structure of DDB1 in Complex with the H-Box Motif of HBX

Summary for 3I7H

Entry DOI	10.2210/pdb3i7h/pdb
Related	2B5M 3I7K 3I7L 3I7N 3I7O 3I7P 3I89 3I8C 3I8E
Descriptor	DNA damage-binding protein 1, X protein (2 entities in total)
Functional Keywords	ddb1, hbv, x protein, h-box motif, cytoplasm, dna damage, dna repair, dna-binding, host-virus interaction, nucleus, phosphoprotein, polymorphism, ubl conjugation, ubl conjugation pathway, activator, apoptosis, mitochondrion, transcription, transcription regulation, protein binding-viral protein complex, protein binding/viral protein
Biological source	Homo sapiens (human) More
Cellular location	Cytoplasm: Q16531
Total number of polymer chains	2
Total formula weight	128978.75
Authors	Li, T.,Robert, E.I.,Breugel, P.C.V.,Strubin, M.,Zheng, N. (deposition date: 2009-07-08, release date: 2009-12-08, Last modification date: 2023-09-06)
Primary citation	Li, T.,Robert, E.I.,van Breugel, P.C.,Strubin, M.,Zheng, N. A promiscuous alpha-helical motif anchors viral hijackers and substrate receptors to the CUL4-DDB1 ubiquitin ligase machinery. Nat.Struct.Mol.Biol., 17:105-111, 2010 Cited by PubMed: 19966799 DOI: 10.1038/nsmb.1719 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.9 Å)

Structure validation