3I54

Crystal structure of MtbCRP in complex with cAMP

Summary for 3I54

Entry DOI	10.2210/pdb3i54/pdb
Related	3I59
Descriptor	Transcriptional regulator, Crp/Fnr family, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE (3 entities in total)
Functional Keywords	mycobacterium tuberculosis, camp receptor protein, allosteric mechanism, dna binding, inhibition, structural genomics, tb structural genomics consortium, tbsgc, dna-binding, transcription, transcription regulation, dna binding protein
Biological source	Mycobacterium tuberculosis
Total number of polymer chains	4
Total formula weight	111706.00
Authors	Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C.,TB Structural Genomics Consortium (TBSGC) (deposition date: 2009-07-03, release date: 2009-09-08, Last modification date: 2024-02-21)
Primary citation	Reddy, M.C.,Palaninathan, S.K.,Bruning, J.B.,Thurman, C.,Smith, D.,Sacchettini, J.C. Structural Insights into the Mechanism of the Allosteric Transitions of Mycobacterium tuberculosis cAMP Receptor Protein. J.Biol.Chem., 284:36581-36591, 2009 Cited by PubMed: 19740754 DOI: 10.1074/jbc.M109.041343 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.2 Å)

Structure validation