3I54

Crystal structure of MtbCRP in complex with cAMP

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Transcriptional regulator, Crp/Fnr family	polymer	249	27597.3	4	UniProt (O69644) Pfam (PF00027) Pfam (PF13545) UniProt (by SIFTS) (P9WMH3)	Mycobacterium tuberculosis
2	E, F, G, H (A, B, C, D)	ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE	non-polymer		329.2	4	Chemie (CMP)
3	I, J, K, L (A, B, C, D)	water	water		18.0	102	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 224 (UniProt: O69644)

PDB	External Database	Details
Met -24	-	expression tag
Gly -23	-	expression tag
Ser -22	-	expression tag
Ser -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
Ser -14	-	expression tag
Ser -13	-	expression tag
Gly -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Gly -9	-	expression tag
Thr -8	-	expression tag
Glu -7	-	expression tag
Asn -6	-	expression tag
Leu -5	-	expression tag
Tyr -4	-	expression tag
Phe -3	-	expression tag
Gln -2	-	expression tag
Ser -1	-	expression tag
His 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	110389.2
Non-Polymers*	Number of molecules	4
	Total formula weight	1316.8
All*	Total formula weight	111706.0

*Water molecules are not included.