3I3A
Structural Basis for the Sugar Nucleotide and Acyl Chain Selectivity of Leptospira interrogans LpxA
Summary for 3I3A
Entry DOI | 10.2210/pdb3i3a/pdb |
Related | 3HSQ 3I3X |
Descriptor | Acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase, S-[2-({N-[(2R)-2-hydroxy-4-{[(S)-hydroxy(methoxy)phosphoryl]oxy}-3,3-dimethylbutanoyl]-beta-alanyl}amino)ethyl] (3R)-3-hydroxydodecanethioate (3 entities in total) |
Functional Keywords | lpxa, leptospira interrogans, leptospira interrogans complex, acyltransferase, lipid a biosynthesis, lipid synthesis, transferase |
Biological source | Leptospira interrogans |
Cellular location | Cytoplasm (By similarity): Q8EZA6 |
Total number of polymer chains | 3 |
Total formula weight | 86318.29 |
Authors | Williams, A.H. (deposition date: 2009-06-30, release date: 2009-09-01, Last modification date: 2024-02-21) |
Primary citation | Robins, L.I.,Williams, A.H.,Raetz, C.R. Structural basis for the sugar nucleotide and acyl-chain selectivity of Leptospira interrogans LpxA. Biochemistry, 48:6191-6201, 2009 Cited by PubMed: 19456129DOI: 10.1021/bi900629e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.12 Å) |
Structure validation
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