3HXZ
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with AlaSA
Summary for 3HXZ
Entry DOI | 10.2210/pdb3hxz/pdb |
Related | 3HXU 3HXV 3HXW 3HXX 3HXY 3HY0 3HY1 |
Descriptor | Alanyl-tRNA synthetase, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total) |
Functional Keywords | aminoacyl-trna synthetase, ligase, protein biosynthesis, nucleotide-binding, amino acid-binding, atp-binding, metal-binding, zinc-finger |
Biological source | Escherichia coli |
Cellular location | Cytoplasm: P00957 |
Total number of polymer chains | 4 |
Total formula weight | 203609.15 |
Authors | Guo, M.,Yang, X.-L.,Schimmel, P. (deposition date: 2009-06-22, release date: 2009-12-15, Last modification date: 2024-02-21) |
Primary citation | Guo, M.,Chong, Y.E.,Shapiro, R.,Beebe, K.,Yang, X.L.,Schimmel, P. Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462:808-812, 2009 Cited by PubMed: 20010690DOI: 10.1038/nature08612 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.99 Å) |
Structure validation
Download full validation report