3HXZ
Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with AlaSA
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Alanyl-tRNA synthetase | polymer | 441 | 49938.1 | 4 | UniProt (P00957) Pfam (PF01411) | Escherichia coli | Alanine-tRNA ligase, AlaRS |
| 2 | E, J, O, R (A, B, C, D) | '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE | non-polymer | 417.4 | 4 | Chemie (A5A) | |||
| 3 | F, G, K, L (A, B) | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID | non-polymer | 238.3 | 4 | Chemie (EPE) | |||
| 4 | H, I, M, N, P... (A, B, C, D) | 2-HYDROXYETHYL DISULFIDE | non-polymer | 154.3 | 8 | Chemie (HED) | |||
| 5 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 2426 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 441 (UniProt: P00957)
| PDB | External Database | Details |
|---|---|---|
| Leu 104 | His 105 | engineered mutation |
| Leu 108 | Gln 109 | engineered mutation |
| Leu 112 | Glu 113 | engineered mutation |
| Ala 237 | Gly 238 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 199752.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 3856.8 | |
| All* | Total formula weight | 203609.1 |
