3HXZ

Crystal Structure of catalytic fragment of E. coli AlaRS G237A in complex with AlaSA

Summary for 3HXZ

Entry DOI	10.2210/pdb3hxz/pdb
Related	3HXU 3HXV 3HXW 3HXX 3HXY 3HY0 3HY1
Descriptor	Alanyl-tRNA synthetase, '5'-O-(N-(L-ALANYL)-SULFAMOYL)ADENOSINE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ... (5 entities in total)
Functional Keywords	aminoacyl-trna synthetase, ligase, protein biosynthesis, nucleotide-binding, amino acid-binding, atp-binding, metal-binding, zinc-finger
Biological source	Escherichia coli
Cellular location	Cytoplasm: P00957
Total number of polymer chains	4
Total formula weight	203609.15
Authors	Guo, M.,Yang, X.-L.,Schimmel, P. (deposition date: 2009-06-22, release date: 2009-12-15, Last modification date: 2024-02-21)
Primary citation	Guo, M.,Chong, Y.E.,Shapiro, R.,Beebe, K.,Yang, X.L.,Schimmel, P. Paradox of mistranslation of serine for alanine caused by AlaRS recognition dilemma. Nature, 462:808-812, 2009 Cited by PubMed: 20010690 DOI: 10.1038/nature08612 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.99 Å)

Structure validation