3HPH
Closed tetramer of Visna virus integrase (residues 1-219) in complex with LEDGF IBD
Summary for 3HPH
Entry DOI | 10.2210/pdb3hph/pdb |
Related | 1K6Y 2B4J 3F9K 3HPG |
Descriptor | Integrase, PC4 and SFRS1-interacting protein, ZINC ION, ... (6 entities in total) |
Functional Keywords | protein-protein complex, tetramer, dna integration, endonuclease, magnesium, metal-binding, multifunctional enzyme, nuclease, nucleotidyltransferase, nucleus, transferase, viral nucleoprotein, virion, dna-binding, host-virus interaction, transcription, transcription regulation, zinc binding, hhcc motif, viral protein, recombination |
Biological source | Maedi visna virus (MVV) More |
Cellular location | Nucleus: O75475 |
Total number of polymer chains | 8 |
Total formula weight | 145232.32 |
Authors | Hare, S.,Wang, J.,Cherepanov, P. (deposition date: 2009-06-04, release date: 2009-07-28, Last modification date: 2023-11-01) |
Primary citation | Hare, S.,Di Nunzio, F.,Labeja, A.,Wang, J.,Engelman, A.,Cherepanov, P. Structural basis for functional tetramerization of lentiviral integrase Plos Pathog., 5:e1000515-e1000515, 2009 Cited by PubMed: 19609359DOI: 10.1371/journal.ppat.1000515 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.64 Å) |
Structure validation
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