3HMO
Crystal structure of human Mps1 catalytic domain in complex with the inhibitor staurosporine
Summary for 3HMO
Entry DOI | 10.2210/pdb3hmo/pdb |
Related | 2ZMC 2ZMD 3HMN 3HMP |
Descriptor | Dual specificity protein kinase TTK, 2-(2-(2-(2-(2-(2-ETHOXYETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHOXY)ETHANOL, STAUROSPORINE, ... (6 entities in total) |
Functional Keywords | mps1, ttk, stu, staurosporine, kinase, atp-binding, nucleotide-binding, phosphoprotein, serine/threonine-protein kinase, tyrosine-protein kinase, transferase |
Biological source | Homo sapiens (human) |
Total number of polymer chains | 1 |
Total formula weight | 40412.02 |
Authors | Chu, M.L.H.,Chavas, L.M.G.,Williams, D.H.,Tabernero, L.,Eyers, P.A. (deposition date: 2009-05-29, release date: 2010-02-02, Last modification date: 2023-09-06) |
Primary citation | Chu, M.L.,Lang, Z.,Chavas, L.M.,Neres, J.,Fedorova, O.S.,Tabernero, L.,Cherry, M.,Williams, D.H.,Douglas, K.T.,Eyers, P.A. Biophysical and X-ray crystallographic analysis of Mps1 kinase inhibitor complexes. Biochemistry, 49:1689-1701, 2010 Cited by PubMed: 20099905DOI: 10.1021/bi901970c PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.4 Å) |
Structure validation
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