3HAV
Structure of the streptomycin-ATP-APH(2")-IIa ternary complex
Summary for 3HAV
Entry DOI | 10.2210/pdb3hav/pdb |
Related | 3ham |
Descriptor | Aminoglycoside phosphotransferase, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ... (5 entities in total) |
Functional Keywords | aminoglycoside, streptomycin, antibiotic resistance, transferase |
Biological source | Enterococcus faecium (Streptococcus faecium) |
Total number of polymer chains | 3 |
Total formula weight | 109533.89 |
Authors | Young, P.G.,Baker, E.N.,Vakulenko, S.B.,Smith, C.A. (deposition date: 2009-05-02, release date: 2009-11-17, Last modification date: 2023-09-06) |
Primary citation | Young, P.G.,Walanj, R.,Lakshmi, V.,Byrnes, L.J.,Metcalf, P.,Baker, E.N.,Vakulenko, S.B.,Smith, C.A. The crystal structures of substrate and nucleotide complexes of Enterococcus faecium aminoglycoside-2''-phosphotransferase-IIa [APH(2'')-IIa] provide insights into substrate selectivity in the APH(2'') subfamily. J.Bacteriol., 191:4133-4143, 2009 Cited by PubMed: 19429619DOI: 10.1128/JB.00149-09 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.45 Å) |
Structure validation
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