3H7R

Crystal structure of the plant stress-response enzyme AKR4C8

Summary for 3H7R

Entry DOI	10.2210/pdb3h7r/pdb
Related	3H7U
Descriptor	Aldo-keto reductase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ACETATE ION, ... (5 entities in total)
Functional Keywords	stress response, aldo-keto reductase, nadp, drought tolerance, oxidoreductase
Biological source	Arabidopsis thaliana (Mouse-ear cress)
Total number of polymer chains	1
Total formula weight	38448.47
Authors	White, S.A.,Simpson, P.J.,Ride, J.P. (deposition date: 2009-04-28, release date: 2009-08-04, Last modification date: 2023-09-06)
Primary citation	Simpson, P.J.,Tantitadapitak, C.,Reed, A.M.,Mather, O.C.,Bunce, C.M.,White, S.A.,Ride, J.P. Characterization of two novel aldo-keto reductases from Arabidopsis: expression patterns, broad substrate specificity, and an open active-site structure suggest a role in toxicant metabolism following stress. J.Mol.Biol., 392:465-480, 2009 Cited by PubMed: 19616008 DOI: 10.1016/j.jmb.2009.07.023 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.4 Å)

Structure validation